HDAC6 Antikörper

Produktnummer ABIN2460227

Der Kaninchen Polyklonal anti-HDAC6 Antikörper wird verwendet zum Nachweis von HDAC6 in Proben von Human und Hund. Er wurde validiert für WB und ELISA.

Kurzübersicht für HDAC6 Antikörper (ABIN2460227)

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HDAC6 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HDAC6.

Anwendungsinformationen

Applikationshinweise: HDAC6 antibody can be used for detection of HDAC6 by ELISA at 1:62500. HDAC6 antibody can be used for detection of HDAC6 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HDAC6 antibody at -20 °C.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: HDAC6

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Molekulargewicht: 16 kDa, 131 kDa

Gen-ID: 10013

UniProt: Q9BRX7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling