COX18
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
Alexa Fluor 647
Applikationshinweise
COX18 antibody can be used for detection of COX18 by ELISA at 1:1562500. COX18 antibody can be used for detection of COX18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Konzentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handhabung
As with any antibody avoid repeat freeze-thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
For short periods of storage (days) store at 4 °C. For longer periods of storage, store COX18 antibody at -20 °C.
Target
COX18
(Cytochrome C Oxidase Assembly Homolog 18 (COX18))
COX18HS antikoerper, BC038311 antikoerper, RGD1559547 antikoerper, COX18 cytochrome c oxidase assembly factor L homeolog antikoerper, COX18, cytochrome c oxidase assembly factor antikoerper, cytochrome c oxidase assembly protein 18 antikoerper, cox18.L antikoerper, COX18 antikoerper, Cox18 antikoerper
Hintergrund
COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).