COX18 Antikörper (Middle Region)

Produktnummer ABIN2786331

Der Kaninchen Polyklonal anti-COX18 Antikörper wird verwendet zum Nachweis von COX18 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für COX18 Antikörper (Middle Region) (ABIN2786331)

Target: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COX18 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: COX18 Antibody - middle region

Sequenz: LCSSFVGLSQ NLLLRSPGFR QLCRIPSTKS DSETPYKDIF AAFNTKFISR

Homologie: Cow: 79%, Dog: 79%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against COX18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COX18

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55716-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu COX18

Target: COX18 (Cytochrome C Oxidase Assembly Homolog 18 (COX18))

Andere Bezeichnung: COX18

Hintergrund:

Background Information: COX18 is required for the insertion of integral membrane proteins into the mitochondrial inner membrane. COX18 is essential for the activity and assembly of cytochrome c oxidase. COX18 plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space.COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2, MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 [PubMed 16212937]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1248 AY957565.1 1-1248 1249-4523 AC095053.3 75071-78345 c

Gene Name: COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)

Alternative Symbols: COX18HS

Protein Name: Mitochondrial inner membrane protein COX18

Molekulargewicht: 37kDa

Gen-ID: 285521

NCBI Accession: NP_776188

UniProt: Q8N8Q8