TRIB2 Antikörper

Produktnummer ABIN2459888

Der Kaninchen Polyklonal Anti-TRIB2-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TRIB2 in Proben von Human, Maus, Ratte und Hund zu detektieren.

Kurzübersicht für TRIB2 Antikörper (ABIN2459888)

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRIB2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIB2.

Anwendungsinformationen

Applikationshinweise: TRIB2 antibody can be used for detection of TRIB2 by ELISA at 1:312500. TRIB2 antibody can be used for detection of TRIB2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIB2 antibody at -20 °C.

Details zu TRIB2

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Andere Bezeichnung: TRIB2

Hintergrund: TRIB2 is one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia.

Molekulargewicht: 39 kDa

Gen-ID: 28951

NCBI Accession: NP_067675

UniProt: Q92519