Aminomethyltransferase Antikörper

Produktnummer ABIN2459732

Der Kaninchen Polyklonal Anti-Aminomethyltransferase-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Aminomethyltransferase in Proben von Human, Maus, Ratte und Hund zu detektieren.

Kurzübersicht für Aminomethyltransferase Antikörper (ABIN2459732)

Target: Aminomethyltransferase (AMT)

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aminomethyltransferase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Aminomethyltransferase Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMT.

Anwendungsinformationen

Applikationshinweise: AMT antibody can be used for detection of AMT by ELISA at 1:12500. AMT antibody can be used for detection of AMT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AMT antibody at -20 °C.

Details zu Aminomethyltransferase

Target: Aminomethyltransferase (AMT)

Andere Bezeichnung: AMT

Hintergrund: The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.The enzyme system for cleavage of glycine (glycine cleavage system, EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase, MIM 238300), H protein (a lipoic acid-containing protein, MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase, MIM 238331). Glycine encephalopathy (GCE, MIM 605899) may be due to a defect in any one of these enzymes.

Molekulargewicht: 44 kDa

Gen-ID: 275

NCBI Accession: NP_000472

UniProt: P48728