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PCDHGC4 Antikörper

Der Kaninchen Polyklonal Anti-PCDHGC4-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, PCDHGC4 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN2459282

Kurzübersicht für PCDHGC4 Antikörper (ABIN2459282)

Target

Alle PCDHGC4 Antikörper anzeigen
PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

Reaktivität

  • 17
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 16
  • 1
Kaninchen

Klonalität

  • 17
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PCDHGC4 Antikörper ist unkonjugiert

Applikation

  • 17
  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Antibody is purified by peptide affinity chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHGC4.
  • Applikationshinweise

    PCDHGC4 antibody can be used for detection of PCDHGC4 by ELISA at 1:1562500. PCDHGC4 antibody can be used for detection of PCDHGC4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Konzentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handhabung

    As with any antibody avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHGC4 antibody at -20 °C.
  • Target

    PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

    Andere Bezeichnung

    PCDHGC4

    Hintergrund

    PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

    Molekulargewicht

    98 kDa

    Gen-ID

    56098

    NCBI Accession

    NP_061751

    UniProt

    Q9Y5F7
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