Sep 15 Antikörper

Produktnummer ABIN2459187

Dieses Anti-Sep 15-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Sep 15 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Sep 15 Antikörper (ABIN2459187)

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sep 15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Sep 15 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Septin 15.

Anwendungsinformationen

Applikationshinweise: Septin 15 antibody can be used for detection of Septin 15 by ELISA at 1:312500. Septin 15 antibody can be used for detection of Septin 15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store Septin 15 antibody at -20 °C.

Details zu Sep 15

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Hintergrund: SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 15 kDa

Gen-ID: 9403

NCBI Accession: NP_004252

UniProt: O60613