G6PC Antikörper

Produktnummer ABIN2458824

Produktdetails anti-G6PC Antikörper

Target: G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser G6PC Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G6PC.

Anwendungsinformationen

Applikationshinweise: G6PC antibody can be used for detection of G6PC by ELISA at 1:62500. G6PC antibody can be used for detection of G6PC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store G6PC antibody at -20 °C.

Details zu G6PC

Target: G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Andere Bezeichnung: G6PC (G6PC Produkte)

Hintergrund: G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molekulargewicht: 40 kDa

Gen-ID: 2538

NCBI Accession: NP_000142

UniProt: P35575

Pathways: Carbohydrate Homeostasis, Cellular Glucan Metabolic Process