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G6PC Antikörper

Dieses Anti-G6PC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von G6PC in WB und ELISA. Geeignet für Human und Hund.
Produktnummer ABIN2458824

Kurzübersicht für G6PC Antikörper (ABIN2458824)

Target

Alle G6PC Antikörper anzeigen
G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

Reaktivität

  • 47
  • 24
  • 23
  • 15
  • 14
  • 13
  • 1
  • 1
  • 1
Human, Hund

Wirt

  • 49
  • 3
Kaninchen

Klonalität

  • 49
  • 3
Polyklonal

Konjugat

  • 20
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser G6PC Antikörper ist unkonjugiert

Applikation

  • 38
  • 24
  • 19
  • 11
  • 11
  • 8
  • 8
  • 4
  • 1
Western Blotting (WB), ELISA
  • Aufreinigung

    Antibody is purified by peptide affinity chromatography method.

    Immunogen

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G6PC.
  • Applikationshinweise

    G6PC antibody can be used for detection of G6PC by ELISA at 1:62500. G6PC antibody can be used for detection of G6PC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Konzentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Handhabung

    As with any antibody avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store G6PC antibody at -20 °C.
  • Target

    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))

    Andere Bezeichnung

    G6PC

    Hintergrund

    G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Molekulargewicht

    40 kDa

    Gen-ID

    2538

    NCBI Accession

    NP_000142

    UniProt

    P35575

    Pathways

    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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