G6PC Antikörper
Kurzübersicht für G6PC Antikörper (ABIN2458824)
Target
Alle G6PC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Aufreinigung
- Antibody is purified by peptide affinity chromatography method.
-
Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G6PC.
-
-
-
-
Applikationshinweise
- G6PC antibody can be used for detection of G6PC by ELISA at 1:62500. G6PC antibody can be used for detection of G6PC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
Konzentration
- 1 mg/mL
-
Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
Handhabung
- As with any antibody avoid repeat freeze-thaw cycles.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store G6PC antibody at -20 °C.
-
-
- G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
-
Andere Bezeichnung
- G6PC
-
Hintergrund
- G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
-
Molekulargewicht
- 40 kDa
-
Gen-ID
- 2538
-
NCBI Accession
- NP_000142
-
UniProt
- P35575
-
Pathways
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
Target
-