DPF3 Antikörper

Produktnummer ABIN2458080

Produktdetails anti-DPF3 Antikörper

Target: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DPF3.

Anwendungsinformationen

Applikationshinweise: DPF3 antibody can be used for detection of DPF3 by ELISA at 1:12500. DPF3 antibody can be used for detection of DPF3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DPF3 antibody at -20 °C.

Details zu DPF3

Target: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Andere Bezeichnung: DPF3 (DPF3 Produkte)

Synonyme: BAF45C antikoerper, CERD4 antikoerper, 2810403B03Rik antikoerper, 6530402L11Rik antikoerper, C78788 antikoerper, cer-d4 antikoerper, si:ch211-268e23.1 antikoerper, wu:fj43h12 antikoerper, double PHD fingers 3 antikoerper, D4, zinc and double PHD fingers, family 3 antikoerper, DPF3 antikoerper, Dpf3 antikoerper, dpf3 antikoerper

Hintergrund: DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.

Molekulargewicht: 40 kDa

Gen-ID: 8110

NCBI Accession: NP_036206

UniProt: Q92784