RRM2 Antikörper (C-Term)
Kurzübersicht für RRM2 Antikörper (C-Term) (ABIN2452118)
Target
Alle RRM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Kreuzreaktivität (Details)
- Not tested in other species.
-
Aufreinigung
- Affinity-purified with the immunogen peptide
-
Sterilität
- Sterile filtered
-
Immunogen
- C-terminal peptide of Human and Mouse RRM2, C-TENSFTLDADF, conjugated with KLH
-
-
-
-
Applikationshinweise
-
1) Western blotting: ~ 1/1,000 dilution
Not tested for other applications -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- PBS (x1), 50 % glycerol. Azide and carrier free.
-
Konservierungsmittel
- Azide free
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Upon receipt aliquot and store at -20 C
-
-
-
: "Identification of ribonucleotide reductase protein R1 as an activator of microtubule nucleation in Xenopus egg mitotic extracts." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4173-87, (2000) (PubMed).
-
-
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
-
Andere Bezeichnung
- RRM2 / RNR-R2
-
Hintergrund
- Betag Ribonucleoside-diphosphate reductase subunit M2 (RRM2, 389 aa, 45 kDa) also known as ribonucleotide reductase subunit R2 (RNR-R2), is a rate-limiting subunit of an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms. Furthermore RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair.
-
UniProt
- P31350
-
Pathways
- Mitotic G1-G1/S Phases
Target
-