RRM2 Antikörper (C-Term)

Produktnummer ABIN6264868

Produktdetails anti-RRM2 Antikörper

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RRM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: RRM2 Antibody detects endogenous levels of total RRM2.

Homologie: Bovine,Horse,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RRM2, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Referenzen für anti-RRM2 Antikörper (ABIN6264868)

Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

Details zu RRM2

Target: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Andere Bezeichnung: RRM2 (RRM2 Produkte)

Synonyme: R2 antikoerper, RR2 antikoerper, RR2M antikoerper, AA407299 antikoerper, rrm2 antikoerper, rr2m antikoerper, cb111 antikoerper, chunp6884 antikoerper, r2 antikoerper, ribonucleotide reductase regulatory subunit M2 antikoerper, ribonucleotide reductase M2 antikoerper, ribonucleotide reductase M2, gene 2 L homeolog antikoerper, ribonucleotide reductase M2, gene 1 antikoerper, ribonucleotide reductase M2 polypeptide antikoerper, RRM2 antikoerper, Rrm2 antikoerper, rrm2.2.L antikoerper, rrm2.1 antikoerper, rrm2 antikoerper

Hintergrund:

Description: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Gene: RRM2

Molekulargewicht: 45kDa

Gen-ID: 6241

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases