KPNA4 Antikörper (full length)

Produktnummer ABIN2452037

Der Ratte Monoklonal Anti-KPNA4-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, KPNA4 in Proben von Maus zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für KPNA4 Antikörper (full length) (ABIN2452037)

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser KPNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: 3D10

Produktdetails anti-KPNA4 Antikörper

Bindungsspezifität: full length

Spezifität: Reactive with human, simian, mouse, rat, hamster, canine and bovine importin a3. This antibody doesn't recognize other importin a family including a4.

Produktmerkmale: The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.

Aufreinigung: Purified

Sterilität: Sterile filtered

Immunogen: Recombinant mouse importin a3 /KPNA4/ Qip 1 (full length)

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: 1. Western blotting: 250~500 fold dilution
2. ELISA
This antibody doesn't work for immunostaining and immunoprecipitation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Konservierungsmittel: Azide free

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: -20 C (For long term storage: -70 C)

Referenzen für anti-KPNA4 Antikörper (ABIN2452037)

Yasuhara, Shibazaki, Tanaka, Nagai, Kamikawa, Oe, Asally, Kamachi, Kondoh, Yoneda: "Triggering neural differentiation of ES cells by subtype switching of importin-alpha." in: Nature cell biology, Vol. 9, Issue 1, pp. 72-9, (2007) (PubMed).

Yoneda: "Nucleocytoplasmic protein traffic and its significance to cell function." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 5, Issue 10, pp. 777-87, (2000) (PubMed).

Miyamoto, Imamoto, Sekimoto, Tachibana, Seki, Tada, Enomoto, Yoneda: "Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors." in: The Journal of biological chemistry, Vol. 272, Issue 42, pp. 26375-81, (1997) (PubMed).

Details zu KPNA4

Target: KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

Andere Bezeichnung: Importin alpha 3 / Qip1KPNA4

Hintergrund: Importin a proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importin a proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin b. Several importin a isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importin a3 (KPNA4, Qip1) is a member of the importin a family of proteins belonging to the Qip1 subfamily.

Pathways: Protein targeting to Nucleus