Chromogranin A Antikörper (N-Term)

Produktnummer ABIN2443753

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Chromogranin A in WB. Es zeigt Reaktivität gegenüber Proben von Human und Säugetier.

Kurzübersicht für Chromogranin A Antikörper (N-Term) (ABIN2443753)

Target: Chromogranin A (CHGA)

Reaktivität: Human, Säugetier

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chromogranin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Chromogranin A Antikörper

Bindungsspezifität: AA 4-16, N-Term

Verwendungszweck: Chromogranin-A (N-term) Rabbit Polyclonal Antibody

Spezifität: The antibody recognizes an epitope in N-terminal (AA 4-16) of Chromogranine-A

Immunogen: N-terminal peptide (AA 4-16)

Anwendungsinformationen

Applikationshinweise: WB 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: If reconstituted with deionized water in 100 μL: WB 1:2000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Haltbarkeit: 24 months

Details zu Chromogranin A

Target: Chromogranin A (CHGA)

Andere Bezeichnung: Chromogranin-A

Hintergrund:

hCGA, parathyroid secretory protein 1, CHGA

Chromogranin-A is a secreted protein known as a ""prohormone"" which is found in endocrine cells and neurons and may be released upon stimulation. It is thought to be involved in the formation of dense core granules, where it may be processed to form the bioactive peptide serpinin, which is thought to regulate the biogenesis of dense core granules in endocrine cells. Chromogranin-A is used as a biomarker in patients with neuroendocrine tumors. Recent publications show that incomplete processing of Chromogranin-A may be linked to diabetic retinopathy

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling