Clathrin Heavy Chain (CLTC) (Heavy Chain) Antikörper

Produktnummer ABIN238388

Produktdetails

Target: Clathrin Heavy Chain (CLTC)

Bindungsspezifität: Heavy Chain

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Spezifität: The antibody recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.

Produktmerkmale: Synonyms: CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain onchromosome 17

Aufreinigung: Ion exchange chromatography

Reinheit: > 95 % (by SDS-PAGE)

Klon: BF-06

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 2-5 μg/mL. Positive control: human blood leukocytes. Immunoprecipitation. Western Blotting. Immunocytochemistry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. Do not freeze.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Antigendetails

Target: Clathrin Heavy Chain (CLTC)

Andere Bezeichnung: Clathrin Heavy Chain (CLTC Produkte)

Hintergrund: Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.Synonyms: CLH17, CLTC, CLTCL2, Clathrin heavy chain on chromosome 17, KIAA0034, Membrane Vesicle Marker

Gen-ID: 1213

UniProt: Q00610