Clathrin Heavy Chain (CLTC) Antikörper

Produktnummer ABIN302098

Produktdetails

Target: Clathrin Heavy Chain (CLTC)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Spezifität: The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa intracellular protein involved in receptor-mediated endocytosis.

Kreuzreaktivität (Details): Human, Porcine, Mouse, Rat, Bovine, Other not determined

Aufreinigung: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Reinheit: > 95 % (by SDS-PAGE)

Klon: BF-06

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 2-5 μg/mL, positive control: human blood leukocytes. Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen

Mac?rek, Zíková, Dráberová, Dráber: "Monoclonal antibody BF-06 against the heavy chain of clathrin." in: Folia biologica, Vol. 49, Issue 6, pp. 238-40, (2004) (PubMed).

Antigendetails

Target: Clathrin Heavy Chain (CLTC)

Andere Bezeichnung: Clathrin heavy chain (CLTC Produkte)

Synonyme: CHC antikoerper, Chc antikoerper, CHC17 antikoerper, CLH-17 antikoerper, CLTCL2 antikoerper, Hc antikoerper, CLTC antikoerper, 3110065L21Rik antikoerper, R74732 antikoerper, F11B9.30 antikoerper, cb1033 antikoerper, cltc antikoerper, wu:fc03e11 antikoerper, wu:fc49a11 antikoerper, wu:fd07f02 antikoerper, clathrin heavy chain antikoerper, Probable clathrin heavy chain 1 antikoerper, putative clathrin heavy chain antikoerper, clathrin heavy chain 1 antikoerper, clathrin heavy chain Chc1 antikoerper, clathrin, heavy polypeptide (Hc) antikoerper, Clathrin, heavy chain antikoerper, clathrin, heavy chain a (Hc) antikoerper, clathrin, heavy chain (Hc) L homeolog antikoerper, CHC1 antikoerper, chc-1 antikoerper, CLTC antikoerper, Chc antikoerper, TP03_0480 antikoerper, LOC5578293 antikoerper, LMJF_36_1630 antikoerper, CpipJ_CPIJ014882 antikoerper, CNJ03270 antikoerper, ATEG_05434 antikoerper, CMU_025200 antikoerper, PMAA_094250 antikoerper, SJAG_02282 antikoerper, Smp_154420.1 antikoerper, PAAG_00730 antikoerper, MCYG_06136 antikoerper, VDBG_05048 antikoerper, MGYG_04658 antikoerper, cgd8_1270 antikoerper, Tc00.1047053506167.50 antikoerper, CHC antikoerper, Cltc antikoerper, AT3G11130 antikoerper, cltca antikoerper, cltc.L antikoerper

Hintergrund: Clathrin heavy chain,Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.,CHC, CLHC, MRD56

Gen-ID: 1213

UniProt: Q00610