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CD73 Antikörper (AA 27-252)

Der Maus Monoklonal Anti-CD73-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, CD73 in Proben von Human zu detektieren.
Produktnummer ABIN238367

Kurzübersicht für CD73 Antikörper (AA 27-252) (ABIN238367)

Target

Alle CD73 (NT5E) Antikörper anzeigen
CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

Reaktivität

  • 185
  • 78
  • 37
  • 19
  • 18
  • 16
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 108
  • 98
  • 22
  • 2
  • 2
  • 1
Maus

Klonalität

  • 137
  • 95
  • 1
Monoklonal

Konjugat

  • 100
  • 21
  • 17
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD73 Antikörper ist unkonjugiert

Applikation

  • 152
  • 125
  • 119
  • 59
  • 46
  • 40
  • 38
  • 27
  • 15
  • 14
  • 14
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon

2B6
  • Bindungsspezifität

    • 16
    • 13
    • 9
    • 9
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-252

    Spezifität

    This antibody is specific for NT5E/CD73.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human.

    Produktmerkmale

    Synonyms: NT5, NTE, NT5E, 5'-nucleotidase

    Aufreinigung

    Protein-G affinity chromatography

    Immunogen

    Recombinant Human CD73 (aa 27-252) purified from E. coli

    Isotyp

    IgG2b
  • Applikationshinweise

    ELISA. Western blot: 1/1,000 - 1/2,000. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4 with 0.09 % Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Haltbarkeit

    12 months
  • Target

    CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))

    Andere Bezeichnung

    CD73

    Hintergrund

    CD73 (Ecto-5'-nucleotidase, 5'-NT) is a membrane-bound glycoprotein that functions to hydrolyze extracellular nucleoside monophosphates into bioactive nucleoside intermediates. This enables the uptake of adenosine, inosine, and guanosine into the cell and their subsequent reconversion into ATP and GTP in the purine salvage pathway. The expression of CD73 on neuronal cells has been described during developmental processes and, on lymphocytes, CD73 serves as a maturation marker, being absent from the surface of both immature B and T cells.Synonyms: 5'-nucleotidase, NT5, NT5E, NTE

    UniProt

    P21589

    Pathways

    Synaptic Membrane, Ribonucleoside Biosynthetic Process
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