CTBP1 Antikörper

Produktnummer ABIN238338

Der Kaninchen Polyklonal anti-CTBP1 Antikörper (ABIN238338) detektiert spezifisch CTBP1 in WB, IF und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CTBP1 Antikörper (ABIN238338)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-CTBP1 Antikörper

Spezifität: The polyclonal antibody reacts with CtBP1, a 49 kDa transcriptional corepressor, that plays a critical role in regulating gene expression.

Aufreinigung: Protein-A affinity chromatography.

Immunogen: Bacterially expressed recombinant human CtBP1.

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Western Blotting (Reducing conditions). Immunocytochemistry (1 μg/mL): acetone/methanol fixation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Andere Bezeichnung: CTBP1

Hintergrund: C-terminal binding protein 1 / brefeldin A (BFA)-dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordonate histone modifications that regulate gene expression.Synonyms: C-terminal-binding protein 1, CTBP

Gen-ID: 1487

NCBI Accession: NP_001319

UniProt: Q13363

Pathways: Retinoic Acid Receptor Signaling Pathway