ERBB3 Antikörper
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- Target Alle ERBB3 Antikörper anzeigen
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ERBB3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding human ErbB-3
- Klon
- DY-7G2
- Isotyp
- IgG1
- Top Product
- Discover our top product ERBB3 Primärantikörper
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anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibody
ERBB3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibodyERBB3 Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB01467 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibodyERBB3 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2E9 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibodyERBB3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) antibodyERBB3 Reaktivität: Human WB, IP, IHC (fro), IHC (f) Wirt: Maus Monoclonal RTJ-1 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibodyERBB3 Reaktivität: Human, Maus WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 661-760) antibodyERBB3 Reaktivität: Human, Maus, Ratte ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1328) antibodyERBB3 Reaktivität: Human, Ratte WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB25837 unconjugated
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- Applikationshinweise
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Kommentare
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Synonyms: Her3
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- Andere Bezeichnung
- ErbB3 (ERBB3 Produkte)
- Hintergrund
- ErbB-3 belongs to the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ErbB receptors (EGFR (ErbB1), ErbB2, ErbB3, and ErbB4) are important regulators of normal growth and differentiation, and they are involved in the pathogenesis of cancer. The 148-kDa trans-membrane polypeptide ErbB-3 has a neuregulin binding domain but not an active kinase domain. Heterodimerisation with EGF receptor family members which possess kinase activity leads to the activation of pathways which indicate cell proliferation or differentiation (1). Over-expression of ErbB-3 has been reported in numerous cancers, including prostate, bladder and breast tumours.
- UniProt
- P21860
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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