MMP2 Antikörper (APMA-Activated)

Produktnummer ABIN233363

Der Maus Monoklonal Anti-MMP2-Antikörper wurde für IHC, IHC (p) und IHC (fro) validiert. Er ist geeignet, MMP2 in Proben von Human zu detektieren.

Kurzübersicht für MMP2 Antikörper (APMA-Activated) (ABIN233363)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MMP2 Antikörper

Bindungsspezifität: APMA-Activated

Spezifität: Recognizes proteins of 72kD and ~66kD which are identified as pro (latent) and active forms of matrix metalloproteinase-2 (MMP-2, also known as 72kD collagenase IV or gelatinase A). No cross-reaction with pro and active forms of other MMPs.

Aufreinigung: Protein G purified

Immunogen: Human APMA-activated native 72kD Gelatinase A.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (2 - 4 μg/mL), IHC-P (2 - 4 μg/mL)

Usage: Immunohistochemistry (Frozen & fixed-paraffin embedded) 2-4 μg/mL g/mL 30 min at RT. Staining of formalin-fixed tissues is improved by boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Conditioned, serum-free medium from (dexamethasone-treated) human fibrosarcoma HT-1080 or endothelial HUVEC cells. Placenta, bladder, breast and ovarian carcinomas. S.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4, 0.2 % BSA, 15 mM sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Andere Bezeichnung: MMP2 / MMP-2

Hintergrund: Name/Gene ID: MMP2
Subfamily: Metallopeptidase M10A
Family: Protease

Synonyms: MMP2, 72 kd type iv collagenase, 72 kDa gelatinase, 72 kd gelatinase, 72 kDa type IV collagenase, CLG4A, CLG4, GelA, Gelatinase A, Matrix metalloproteinase-2, MMP-2, MONA, Neutrophil gelatinase, TBE-1, Tbe-1 metalloprotease, Collagenase type IV-A, Matrix metalloproteinase-II, MMP-II

Gen-ID: 4313

UniProt: P08253

Pathways: Activation of Innate immune Response