Lamin A/C Antikörper (N-Term)
Kurzübersicht für Lamin A/C Antikörper (N-Term) (ABIN228720)
Target
Alle Lamin A/C (LMNA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Detects endogenous levels of the small fragment of lamin A when cleaved by caspase-6 at Asp230. It is a marker of caspase-6 activity. Detects the small fragment of lamin A/C only when cleaved at Asp230. Does not cross-react with full length lamin A (nor with lamin C). Species cross-reactivity: Mouse and rat.
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Aufreinigung
- Purified
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Immunogen
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Synthetic peptide corresponding to N-terminal residues adjacent to Asp230 in human lamin A.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG1
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Applikationshinweise
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Approved: ICC, IF (1:1000), WB (1:1000)
Usage: Western Blot: 1:1000. Immunocytochemistry (ABC) 1:1000. Immunocytochemistry (IF) 1:1000. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol, 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Lamin A/C (LMNA)
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Andere Bezeichnung
- LMNA / Lamin A/C
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Hintergrund
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Name/Gene ID: LMNA
Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1
This antibody detects: LMNA / Lamin A+C -
Gen-ID
- 4000
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UniProt
- P02545
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
Target
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