DRD4 Antikörper (AA 176-185)

Produktnummer ABIN227849

Der Kaninchen Polyklonal Anti-DRD4-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, DRD4 in Proben von Ratte zu detektieren.

Kurzübersicht für DRD4 Antikörper (AA 176-185) (ABIN227849)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DRD4 Antikörper

Bindungsspezifität: AA 176-185

Spezifität: Recognizes rat D4 Dopamine Receptor (Ac-176-185) 100 % D4 Dopamine Receptor 60 % D1 Dopamine Receptor (9-21) 0 % D1 Dopamine Receptor 0 % D2 Dopamine Receptor (272-282) 0 % D2 Dopamine Receptor 0 % D3 Dopamine Receptor (2-10) 0 % D3 Dopamine Receptor 0 % D5 Dopamine Receptor (23-35) 0 % D5 Dopamine Receptor 0 %.

Aufreinigung: Delipidated and defibrinated

Immunogen: D4 (Ac-176-185) covalently attached to a carrier protein.

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IHC, WB

Usage: Suitable for immunocytochemical detection of the D4 dopamine receptor. Characterized by immunocytochemical, western immunoblot and ELISA techniques. This antiserum has been found to stain specific cells in various regions of PLP fixed rat brain sections at a dilution of 1:10000. This includes the glomeruli of the olfactory bulb, staining of cortex layer 4 and dendritic staining in cortex layers 2 and 3. In layer 5 of the cortex, apical dendrites of many neurons were stained. In the hippocampus, diffuse immunoreactivity was observed in the molecular layer of the dentate gyrus, with fine dots associated with many neurons in the granule cell layer. Western immunoblots using whole rat brain homogenate resulted in a single wide band being detected at ~48-53kD at 1:500 dilution.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: deionized water

Konzentration: Lot specific

Buffer: Lyophilized.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Andere Bezeichnung: DRD4 / Dopamine Receptor D4

Hintergrund: Name/Gene ID: DRD4
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD4, D(4) dopamine receptor, D4DR, D(2C) dopamine receptor, D4 dopamine receptor, Dopamine receptor D4, Dopamine 4 receptor, Dopamine D4 receptor

Gen-ID: 1815

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity