DRD4 Antikörper (AA 355-404)

Produktnummer ABIN1535585

Der Kaninchen Polyklonal anti-DRD4 Antikörper (ABIN1535585) detektiert spezifisch DRD4 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DRD4 Antikörper (AA 355-404) (ABIN1535585)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-DRD4 Antikörper

Bindungsspezifität: AA 355-404

Verwendungszweck: D4DR Antibody

Spezifität: D4DR Polyclonal Antibody detects endogenous levels of D4DR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Andere Bezeichnung: DRD4

Hintergrund:

Synonyms: DRD4, D(4) dopamine receptor, D(2C) dopamine receptor, Dopamine D4 receptor

Background: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats. [provided by RefSeq, Jul 2008],

Gene Name: DRD4

Protein Name: D(4) dopamine receptor

Molekulargewicht: 48 kDa

Gen-ID: 1815

OMIM: 126452

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity