RAD9A Antikörper (AA 1125-1139)

Produktnummer ABIN225443

Der Kaninchen Polyklonal Anti-RAD9A-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, RAD9A in Proben von Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für RAD9A Antikörper (AA 1125-1139) (ABIN225443)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RAD9A Antikörper

Bindungsspezifität: AA 1125-1139

Spezifität: Detects Saccharomyces cerevisiae Rad9, a protein involved in the DNA damage checkpoint. In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the ortholog of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability. Is pan reactive with both the phosphorylated and non-phosphorylated forms of this protein.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1:2000 - 1:4000), WB (1:50 - 1:250)

Usage: Western Blot: LS-C42615 detects a band of approximately 60kD.

Kommentare:

Target Species of Antibody: Yeast

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Andere Bezeichnung: RAD9A / RAD9

Hintergrund: Name/Gene ID: RAD9A

Synonyms: RAD9A, HRAD9, RAD9, RAD9 homolog, RAD9 (S. pombe) homolog, RAD9 homolog A (S. pombe)

Gen-ID: 5883

UniProt: Q99638

Pathways: Positive Regulation of Response to DNA Damage Stimulus