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LYZ Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch LYZ in WB, IP und IA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN2192194

Kurzübersicht für LYZ Antikörper (ABIN2192194)

Target

Alle LYZ Antikörper anzeigen
LYZ (Lysozyme (LYZ))

Reaktivität

  • 97
  • 35
  • 29
  • 11
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 95
  • 25
  • 3
  • 1
Kaninchen

Klonalität

  • 88
  • 35
Polyklonal

Konjugat

  • 69
  • 11
  • 10
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LYZ Antikörper ist unkonjugiert

Applikation

  • 77
  • 52
  • 31
  • 31
  • 29
  • 15
  • 14
  • 13
  • 13
  • 11
  • 8
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunoassay (IA)
  • Sterilität

    0.2 μm filtered
  • Applikationshinweise

    For Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

    Haltbarkeit

    12 months
  • Ibrahim, Aoki, Pellegrini: "Strategies for new antimicrobial proteins and peptides: lysozyme and aprotinin as model molecules." in: Current pharmaceutical design, Vol. 8, Issue 9, pp. 671-93, (2002) (PubMed).

    Cole, Liao, Stuchlik, Tilan, Pohl, Ganz: "Cationic polypeptides are required for antibacterial activity of human airway fluid." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 12, pp. 6985-91, (2002) (PubMed).

  • Target

    LYZ (Lysozyme (LYZ))

    Andere Bezeichnung

    Lysozyme

    Hintergrund

    Lysozyme is a 14 kd enzyme directed against the b 1 a 4 glycosidic bond between N-acetylglucosamine and N-acetylmuramic acid residues that make up peptidoglycan. Lysozyme is an antimicrobial protein secreted by polymorphonuclear leukocytes and is widely distributed in secretions such as airway secretions and nasal fluid whereas it is the most effective antimicrobial protein. It is also produced by monocytes, macrophages and epithelial cells. Lysozyme is able to kill bacteria by enzymatic lysis of bacterial cell walls and by a nonenzymatic mechanism. Allthough lysozyme is highly active against many gram-positive bacteria it is ineffective against gram-negative bacteria unless potentiated by certain cofactors (lactoferrin, antibody-complement or hydrogen peroxide-ascorbic acid). Next to its antimicrobial activity lysozyme has many other physiological functions including inactivation of certain viruses, important roles in surveillance of membranes of mammalian cells, immune regulatory activity, anti-inflammatory and antitumor activity
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