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C3 Antikörper (Complement Component 3) Primary Antibody

C3 Reaktivität: Schwein FACS Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN2192159
$659.59
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle C3 Antikörper anzeigen
    C3
    Reaktivität
    • 110
    • 57
    • 36
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Schwein
    Wirt
    • 70
    • 58
    • 36
    • 8
    • 8
    • 7
    Kaninchen
    Klonalität
    • 141
    • 45
    Polyklonal
    Konjugat
    • 93
    • 25
    • 25
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser C3 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 63
    • 44
    • 37
    • 34
    • 34
    • 29
    • 28
    • 26
    • 19
    • 16
    • 13
    • 12
    • 9
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Sterilität
    0.2 μm filtered
  • Applikationshinweise
    For flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Positive Red Blood Cells control
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Pérez de la Lastra, Harris, Hinchliffe, Holt, Rushmere, Morgan: "Pigs express multiple forms of decay-accelerating factor (CD55), all of which contain only three short consensus repeats." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 5, pp. 2563-73, (2000) (PubMed).

  • Target
    C3
    Abstract
    C3 Produkte
    Synonyme
    AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, AI255234, HSE-MSF, Plp, C3, C3-1, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11, C3d, asp, cpamd1, c3, complement C3, complement component 3, complement component c3a, duplicate 1, complement component 3 L homeolog, complement component C3, complement C3-like, C3, c3a.1, c3.L, LOC443475, c3, c3-1, LOC100060539
    Hintergrund
    The polyclonal antibody recognizes pig complement component C3. The complement system is an important part of the humoral response in innate immunity, consisting of three different pathways. The third complement component, C3, is central to the classical, alternative and lectin pathways of complement activation. Activation products of the complement cascade contain neo-epitopes that are not present in the individual native components. The complement factor C3 consists of an alpha- and a beta-chain. The synthesis of C3 is tissue-specific and is modulated in response to a variety of stimulatory agents. C3 is the most abundant protein of the complement system with serum protein levels of about 1.3 mg/mL. An inherited deficiency of C3 predisposes the person to frequent assaults of bacterial infections. In ulcerative colitis, and idiopathic chronic inflammatory bowel disease, the deposition of C3 in the diseased mucosa has been reported. Proteolysis by certain enzymes results in the cleavage of C3 into C3a and C3b. C3b becomes attached to immune complexes and is further cleaved into iC3b, C3c, C3dg and C3f. Aliases Complement component C3 Immunogen Purified Pig C3
    Pathways
    Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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