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CD55 Antikörper

Der Maus Monoklonal Anti-CD55-Antikörper wurde für WB und IA validiert. Er ist geeignet, CD55 in Proben von Schwein zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2192138

Kurzübersicht für CD55 Antikörper (ABIN2192138)

Target

Alle CD55 Antikörper anzeigen
CD55 (Complement Decay-Accelerating Factor (CD55))

Reaktivität

  • 147
  • 32
  • 8
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
Schwein

Wirt

  • 102
  • 72
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
Maus

Klonalität

  • 122
  • 66
  • 2
Monoklonal

Konjugat

  • 99
  • 16
  • 16
  • 11
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD55 Antikörper ist unkonjugiert

Applikation

  • 106
  • 101
  • 46
  • 45
  • 38
  • 26
  • 25
  • 25
  • 17
  • 14
  • 14
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoassay (IA)

Klon

PD2
  • Sterilität

    0.2 μm filtered
  • Applikationshinweise

    For Western blotting and flow cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Porcine platelet lysate control

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

    Haltbarkeit

    12 months
  • Pérez de la Lastra, Harris, Hinchliffe, Holt, Rushmere, Morgan: "Pigs express multiple forms of decay-accelerating factor (CD55), all of which contain only three short consensus repeats." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 5, pp. 2563-73, (2000) (PubMed).

  • Target

    CD55 (Complement Decay-Accelerating Factor (CD55))

    Andere Bezeichnung

    Complement Decay Accelerating Factor

    Hintergrund

    The monoclonal antibody PD2 recognizes pig complement decay accelerating factor (DAF), also designated as CD55. Cells express on their surface several proteins which protect against complement attack, namely C receptor I (CR1), decay accelerating factor (DAF), membrane cofactor protein (MCP) and CD59. CR1, DAF and MCP regulate the activation pathways of complement by either accelerating decay of the C3 and C5 convertase (CR1, DAF), or acting as cofactors for the serine protease factor I, which cleaves and irreversibly inactivates C3b (CR1, MCP). Pig DAF (CD55) is a 45-52 kDa transmembrane protein that binds C3b and C4b to inhibit formation and half-life of the C3 convertases. DAF is broadly distributed among cells in contact with serum, including both haematopoietic and nonhaematopoietic cells. Although DAF does not have an essential role in controlling hemolysis of erythrocytes, it has an important role in regulation of the deposition of C3 on nucleated cells. Together with other complement regulators DAF protects self cells from autologous complement- mediated injury. DAF cooperates with CD46 in circumventing autologous C3 deposition, while CD59 inhibits the pathway at the critical end-point. Aliases DAF, CD55 Immunogen Pig DAF-Ig fusion protein

    Pathways

    Komplementsystem, Regulation of Leukocyte Mediated Immunity
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