CD59 Antikörper
(1 reference)-
- Target Alle CD59 Antikörper anzeigen
- CD59
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD59 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Blocking Antibody (Inhibition)
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Low endotoxin level
- Klon
- MEM-43
- Top Product
- Discover our top product CD59 Primärantikörper
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anti-CD59 (CD59) (AA 31-111) antibody
CD59 Reaktivität: Human FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 8D2B8 unconjugated
anti-CD59 (CD59) (AA 74-110) antibodyCD59 Reaktivität: Human FACS, WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB56691 unconjugated
anti-CD59 (CD59) antibodyCD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 unconjugated
anti-CD59 (CD59) antibodyCD59 Reaktivität: Human, Maus FACS, WB, IP, IHC (p) Wirt: Maus Monoclonal MEM-43-5 unconjugated
anti-CD59 (CD59) (AA 31-111) antibodyCD59 Reaktivität: Human FACS, WB, IHC, ELISA, IF/ICC Wirt: Maus Monoclonal unconjugated
anti-CD59 (CD59) (AA 23-105) antibodyCD59 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD59 (CD59) (AA 1-128) antibodyCD59 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3G6 unconjugated
anti-CD59 (CD59) (AA 26-102) antibodyCD59 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD59 (CD59) antibody (Biotin)CD59 Reaktivität: Human FACS, IP, IHC (p) Wirt: Maus Monoclonal MEM-43 Biotin
anti-CD59 (CD59) antibody (FITC)CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-43 FITC
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- Applikationshinweise
- For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. For neutralization of biological activity dilutions have to be made according to the amounts endotoxin to be inactivated.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS and 0.1 % bovine serum albumin with low endotoxin level.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- Haltbarkeit
- 12 months
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: "Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14." in: Cellular signalling, Vol. 15, Issue 9, pp. 861-9, (2003) (PubMed).
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: "Lipopolysaccharide signal transduction in oral keratinocytes--involvement of CD59 but not CD14." in: Cellular signalling, Vol. 15, Issue 9, pp. 861-9, (2003) (PubMed).
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- Target
- CD59
- Andere Bezeichnung
- CD59 (CD59 Produkte)
- Hintergrund
- The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitope (W40, R-53) on CD59 Molecule.
- Pathways
- Komplementsystem
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