C5 Antikörper

Produktnummer ABIN2191951

Dieses Maus Monoklonal-Antikörper erkennt spezifisch C5 in WB und IA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für C5 Antikörper (ABIN2191951)

Target: C5 (Complement Component 5 (C5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoassay (IA)

Klon: 568

Produktdetails anti-C5 Antikörper

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Applikationshinweise: It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Haltbarkeit: 12 months

Referenzen für anti-C5 Antikörper (ABIN2191951)

Mollnes, Klos, Tschopp: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: c5/c5b

Hintergrund: Monoclonal antibody 568 reacts with an epitope on C5 and on C5b. C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.

Pathways: Komplementsystem, Carbohydrate Homeostasis