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FABP1 Antikörper (Fatty Acid Binding Protein 1, Liver) Primary Antibody

FABP1 Reaktivität: Human IA, FACS, IHC (p), WB Wirt: Maus Monoclonal L2B10 unconjugated
Pubmed (1 reference)
Produktnummer ABIN2191917
$605.98
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle FABP1 Antikörper anzeigen
    FABP1
    Reaktivität
    • 74
    • 29
    • 19
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 31
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 65
    • 31
    Monoklonal
    Konjugat
    • 49
    • 20
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FABP1 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 43
    • 27
    • 17
    • 14
    • 11
    • 10
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunoassay (IA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Kreuzreaktivität (Details)
    Cross reactivity: : Baboon L-FABP : Yes, Dog L-FABP : Yes, Rat L-FABP : Yes, Swine L-FABP : Yes, Human H-FABP Weak
    Sterilität
    0.2 μm filtered
    Klon
    L2B10
    Isotyp
    IgG2b
  • Applikationshinweise
    For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Bax, Siersema, Haringsma, Kuipers, Vos, Van Dekken, Van Vliet, Kusters: "High-grade dysplasia in Barrett's esophagus is associated with increased expression of calgranulin A and B." in: Scandinavian journal of gastroenterology, Vol. 42, Issue 8, pp. 902-10, (2007) (PubMed).

  • Target
    FABP1
    Andere Bezeichnung
    Liver Fatty Acid Binding Protein (FABP1 Produkte)
    Synonyme
    FABPL, L-FABP, KAT4, KATIV, mitAAT, Fabpl, Fabplg, SCP, SCP., p14, FABP1, FABP, LFABP, liver, fabp1, Fabp1, FABP-1, FABPpm, mAspAT, fatty acid binding protein 1, glutamic-oxaloacetic transaminase 2, fatty acid binding protein 1, liver, fatty acid binding protein 1a, liver, fatty acid-binding protein, liver, FABP1, GOT2, Fabp1, fabp1a, LOC100726384
    Hintergrund
    The monoclonal antibody L2B10 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin. The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium. The monoclonal antibody L2B10 is useful to detect ischemic areas of human liver. Furthermore, the antibody can be used for the purification of human L-FABP. Aliases FABP1
    Pathways
    Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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