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Vinexin Antikörper (Sorbin and SH3 Domain Containing 3) AA 401-500 (Cy5.5) Primary Antibody

Sorbs3 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN2180079
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle Vinexin (Sorbs3) Antikörper anzeigen
    Vinexin (Sorbs3)
    Bindungsspezifität
    • 14
    • 7
    • 1
    • 1
    AA 401-500
    Reaktivität
    • 22
    • 4
    • 2
    Human
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Vinexin Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 12
    • 12
    • 11
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Vinexin
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    Vinexin (Sorbs3)
    Andere Bezeichnung
    Vinexin (Sorbs3 Produkte)
    Synonyme
    zgc:113031, si:dkey-162f21.1, SCAM-1, SH3P3, Sh3d4, vinexin-g, SCAM1, SH3D4, sorbin and SH3 domain containing 3, SORBS3, sorbs3, Sorbs3
    Hintergrund

    Vinexin is a 671 amino acid protein that is expressed as two isoforms, designated Vinexin alpha and Vinexin beta. Localized to cell junctions in both the cytoplasm and the cytoskeleton, Vinexin alpha functions to promote Actin stress fiber formation, playing an important role in modification of the Actin cytoskeleton. Like Vinexin alpha, Vinexin beta is localized to cell junctions in the cytoplasm, but is also found in the nucleus where it plays an important role in cell spreading and in activation of the JNK pathway in response to EGF stimulation. Although Vinexin alpha and Vinexin beta have different roles within the cell, both proteins contain three SH3 domains in their carboxy terminus and are expressed in a variety of tissues, including placenta, heart, liver, brain, pancreas and skeletal muscle. Together, Vinexin alpha and Vinexin beta are involved in cell-cell adhesion, signal transduction and cytoskeletal organization throughout the cell.

    Subcellular location: Cell membrane

    Synonyms: SCAM 1, SCAM1, SH3 containing adapter molecule 1, SH3 domain containing adapter molecule 1, SH3D4, Sorbin and SH3 domain containing 3, Sorbin and SH3 domain containing protein 3, Sorbs3, Vinexin alpha, Vinexin, Vinexin beta (SH3 containing adaptor molecule 1).

    Pathways
    MAPK Signalweg
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