CTNNA3 Antikörper (AA 131-230)

Produktnummer ABIN2173430

Der Kaninchen Polyklonal Anti-CTNNA3-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC validiert. Er ist geeignet, CTNNA3 in Proben von Human zu detektieren.

Kurzübersicht für CTNNA3 Antikörper (AA 131-230) (ABIN2173430)

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTNNA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-CTNNA3 Antikörper

Bindungsspezifität: AA 131-230

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTNNA3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CTNNA3

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Andere Bezeichnung: CTNNA3

Hintergrund:

Synonyms: 4930429L08Rik, 4933408A16, Alpha catenin like protein, Alpha T catenin, Alpha T-catenin, Cadherin associated protein, Cadherin-associated protein, Catenin alpha 3, Catenin alpha-3, Catna3, CTNA3_HUMAN, CTNNA3, MGC26194, MGC75041, OTTHUMP00000019684, OTTMUSP00000028119, OTTMUSP00000028120, RP11-433J16.1, VR22.

Background: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.