COX IV Antikörper (AA 51-169)

Produktnummer ABIN2173360

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COX IV in WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus und wurde in 6+ Publikationen erwähnt.

Kurzübersicht für COX IV Antikörper (AA 51-169) (ABIN2173360)

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX IV Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-COX IV Antikörper

Bindungsspezifität: AA 51-169

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COX4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-COX IV Antikörper (ABIN2173360)

Wang, Zhang, Li, Yue, Xu, Zhang, Yung, Li: "Fine particulate matter induces mitochondrial dysfunction and oxidative stress in human SH-SY5Y cells." in: Chemosphere, Vol. 218, pp. 577-588, (2019) (PubMed).

Wu, Luo, Zhou, Cheng, Lin, Liu, Liu, Li, Yang: "Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol." in: Biochimica et biophysica acta, Vol. 1863, Issue 9, pp. 2307-2318, (2017) (PubMed).

Kouam, Yuan, Njayou, He, Tsayem, Oladejo, Song, Moundipa, Gao: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).

Gao, Wen, Zhou, Feng: "De-methylation of displacement loop of mitochondrial DNA is associated with increased mitochondrial copy number and nicotinamide adenine dinucleotide subunit 2 expression in colorectal cancer." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 7033-8, (2016) (PubMed).

Wang, He, Wu, Li, Gao, Zeng: "Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice." in: PeerJ, Vol. 3, pp. e822, (2015) (PubMed).

Details zu COX IV

Target: COX IV (COX4I1) (Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1))

Andere Bezeichnung: COX4

Hintergrund:

Synonyms: COX4, COXIV, COX4-1, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1, COX4I1

Background: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Gen-ID: 1327

UniProt: P13073

Pathways: Proton Transport