GJB2 Antikörper (Cytoplasmic Domain)

Produktnummer ABIN215079

Dieses Anti-GJB2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GJB2 in WB, ELISA, IHC, IF und IHC (fro). Geeignet für Ratte.

Kurzübersicht für GJB2 Antikörper (Cytoplasmic Domain) (ABIN215079)

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GJB2 Antikörper

Bindungsspezifität: Cytoplasmic Domain

Spezifität: Reacts predominantly with Connexin 26. By immunoblot analysis, a 26kD protein from mouse liver membrane, mouse brain extract and rat brain extract was detected (note: samples were not boiled prior to running SDS-PAGE). A few cross-reactive bands were detected in the 45-50kD range. The identity of these proteins has yet to be confirmed, however, it is possible these bands represent dimeric forms of the Connexin 26 protein. Immunohistochemical staining of frozen sections of human cochlea showed positive reactivity for Connexin 26.

Aufreinigung: Immunoaffinity purified

Immunogen: Peptide corresponding to a portion of the cytoplasmic loop of rat connexin 26.

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IF, IHC, IHC-Fr, WB

Usage: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. ELISA: 0.1-1.0 mg/mL. Western Blot: 0.5 mg/mL. Immunohistochemistry (frozen): 10 mg/mL. Immunofluorescence.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Details zu GJB2

Target: GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

Andere Bezeichnung: GJB2 / CX26 / Connexin 26

Hintergrund: Name/Gene ID: GJB2
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A

Gen-ID: 2706

UniProt: P29033

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization