CCL3 Antikörper

Produktnummer ABIN2146633

Der Kaninchen Polyklonal anti-CCL3 Antikörper (ABIN2146633) detektiert spezifisch CCL3 in WB, ELISA und InhibAb. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für CCL3 Antikörper (ABIN2146633)

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Produktdetails anti-CCL3 Antikörper

Aufreinigung: Purified

Immunogen: MIP1 alpha antibody was raised in rabbit using highly pure recombinant rat MIP1 alpha as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-2 μg/mL, Inhibition: 8-10 μg/mL, WB: 0.1-0.2 μg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water to a concentration of > 0.2 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from 0.5 x PBS, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Andere Bezeichnung: MIP1 alpha

Hintergrund: Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ, with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes.

Molekulargewicht: 7.8 kDa (predicted detection band MW)

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagie