M-CSF/CSF1 Antikörper
Kurzübersicht für M-CSF/CSF1 Antikörper (ABIN2146084)
Target
Alle M-CSF/CSF1 (CSF1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Purified
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Immunogen
- M-CSF antibody was raised in rabbit using highly pure recombinant human M-CSF as the immunogen.
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Applikationshinweise
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ELISA: 0.5-2 μg/mL, Inhibition: 0.02-0.03 μg/mL, WB: 0.1-0.2 μg/mL
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute with water to a concentration of 0.1 - 1.0 mg/mL.
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Konzentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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Andere Bezeichnung
- M-CSF
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Hintergrund
- M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness, and male and female fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. The human is reactive in Mouse systems, but the Mouse molecule exhibits no activity on human cells.
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Molekulargewicht
- 18.1 kDa (predicted detection band MW)
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Pathways
- RTK Signalweg
Target
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