PDE8B Antikörper (Internal Region)

Produktnummer ABIN213536

Produktdetails anti-PDE8B Antikörper

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)

Marke: IHC-plus™

Spezifität: Human PDE8B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Dog, Horse (94%) Mouse, Rat, Bat, Elephant, Pig (88%) Opossum, Platypus (81%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic 16 amino acid peptide from internal region of human PDE8B. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Dog, Horse (94%), Mouse, Rat, Bat, Elephant, Pig (88%), Opossum, Platypus (81%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDE8B

Target: PDE8B (phosphodiesterase 8B (PDE8B))

Andere Bezeichnung: PDE8B (PDE8B Produkte)

Synonyme: PDE8B antikoerper, ADSD antikoerper, PPNAD3 antikoerper, B230331L10Rik antikoerper, C030047E14Rik antikoerper, RNPDE8B antikoerper, phosphodiesterase 8B antikoerper, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antikoerper, PDE8B antikoerper, LOC100468338 antikoerper, pde8b antikoerper, Pde8b antikoerper

Hintergrund: Name/Gene ID: PDE8B
Subfamily: PDE - cAMP-specific, high affinity
Family: Phosphodiesterase

Synonyms: PDE8B, ADSD, HsPDE8B, PPNAD3, Phosphodiesterase 8B

Gen-ID: 8622

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process