ERBB3 Antikörper (AA 1295-1323)
Kurzübersicht für ERBB3 Antikörper (AA 1295-1323) (ABIN211920)
Target
Alle ERBB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1295-1323
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Spezifität
- Recognizes erbB-3 (185kD). Does not cross-react with erbB-1 (EGFR) and erbB-2/HER-2 Species cross-reactivity: Human. Species sequence Homology: Mouse, rat and bovine.
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Aufreinigung
- Protein A purified
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Immunogen
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Recombinant rat erbB-3/HER-3 oncoprotein expressed in insect cells and purified by metal chelating chromatography. Epitope maps between aa1295-1323 of human erbB-3.
Type of Immunogen: Recombinant protein -
Isotyp
- IgG2a kappa
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Applikationshinweise
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Approved: ICC, IHC (1:50 - 1:100), IP, WB (0.1 - 2 μg/mL)
Usage: Suitable for use in Immunocytochemistry, Western Blot, Immunoprecipitation and Immunohistochemistry. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: 4 μg antibody immunoprecipitates erbB-3 from human MDA and MCF-7 RIPA lysates. Immunohistochemistry: 1:50-1:100 dilution of a previous lot detected erbB-3 membrane staining in human normal and carcinoma breast tissue. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM PBS, pH 7.4, 0.2 % BSA, 0.09 % sodium azide, 40 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Andere Bezeichnung
- HER3 / ERBB3
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Hintergrund
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Name/Gene ID: ERBB3
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3 -
Gen-ID
- 2065
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UniProt
- P21860
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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