MPL Antikörper (AA 615-628)

Produktnummer ABIN211285

Produktdetails anti-MPL Antikörper

Target: MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))

Bindungsspezifität: AA 615-628

Reaktivität: Human, Maus, Hamster, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Spezifität: Recognizes glycosylated and unglycosylated human TPO receptor/c-Mpl, Mr 70kD. Species cross-reactivity: mouse. Species sequence Homology: mouse - 100 % .

Homologie: Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%) Elephant, Rabbit (93%) Panda, Bovine, Pig (86%).

Aufreinigung: Protein A purified

Immunogen: Synthetic peptide corresponding to amino acids 615-628 of human TPO (thrombopoietin) receptor [C-ANHSYLPLSYWQQP] (KLH-conjugated). Species sequence Homology: Mouse - 100%. Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%), Elephant, Rabbit (93%), Panda, Bovine, Pig (86%).

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IP, WB (0.25 - 1 μg/mL)

Usage: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunohistochemistry: Stains megakaryocytes in bone marrow biopsy sections. Immunoprecipitation: 5 μg immunoprecipitates TPO receptor from 500 μg of DAMI RIPA lysate.

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu MPL

Target: MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))

Andere Bezeichnung: CD110 / MPL (MPL Produkte)

Synonyme: C-MPL antikoerper, CD110 antikoerper, MPLV antikoerper, THCYT2 antikoerper, TPOR antikoerper, TPO-R antikoerper, c-mpl antikoerper, c-mpl-I antikoerper, c-mpl-II antikoerper, hlb219 antikoerper, MPL antikoerper, mpll antikoerper, tpor antikoerper, tpor.b antikoerper, MPL proto-oncogene, thrombopoietin receptor antikoerper, myeloproliferative leukemia virus oncogene antikoerper, MPL antikoerper, Mpl antikoerper, mpl antikoerper

Hintergrund: Name/Gene ID: MPL

Synonyms: MPL, CD110 antigen, C-MPL, CD110, MPLV, Proto-oncogene c-Mpl, TPOR, TPO-R, THCYT2, Thrombopoietin receptor

Gen-ID: 4352

UniProt: P40238

Pathways: JAK-STAT Signalweg