MPL Antikörper (AA 615-628)
Kurzübersicht für MPL Antikörper (AA 615-628) (ABIN211285)
Target
Alle MPL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 615-628
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Spezifität
- Recognizes glycosylated and unglycosylated human TPO receptor/c-Mpl, Mr 70kD. Species cross-reactivity: mouse. Species sequence Homology: mouse - 100 % .
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Homologie
- Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%) Elephant, Rabbit (93%) Panda, Bovine, Pig (86%).
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Aufreinigung
- Protein A purified
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Immunogen
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Synthetic peptide corresponding to amino acids 615-628 of human TPO (thrombopoietin) receptor [C-ANHSYLPLSYWQQP] (KLH-conjugated). Species sequence Homology: Mouse - 100%. Percent identity by BLAST analysis: Human, Monkey, Mouse, Hamster (100%), Elephant, Rabbit (93%), Panda, Bovine, Pig (86%).
Type of Immunogen: Synthetic peptide - KLH conjugated -
Isotyp
- IgG
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Applikationshinweise
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Approved: IHC, IP, WB (0.25 - 1 μg/mL)
Usage: Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunohistochemistry: Stains megakaryocytes in bone marrow biopsy sections. Immunoprecipitation: 5 μg immunoprecipitates TPO receptor from 500 μg of DAMI RIPA lysate.
Not recommended for: IHC-P -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide, 30 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- MPL (Myeloproliferative Leukemia Virus Oncogene (MPL))
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Andere Bezeichnung
- CD110 / MPL
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Hintergrund
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Name/Gene ID: MPL
Synonyms: MPL, CD110 antigen, C-MPL, CD110, MPLV, Proto-oncogene c-Mpl, TPOR, TPO-R, THCYT2, Thrombopoietin receptor -
Gen-ID
- 4352
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UniProt
- P40238
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Pathways
- JAK-STAT Signalweg
Target
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