Androgen Receptor Antikörper (pSer213)

Produktnummer ABIN207872

Der Maus Monoklonal Anti-Androgen Receptor-Antikörper wurde für WB validiert. Er ist geeignet, Androgen Receptor in Proben von Human und Affe zu detektieren.

Kurzübersicht für Androgen Receptor Antikörper (pSer213) (ABIN207872)

Target: Androgen Receptor (AR)

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Androgen Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 156C135-2

Produktdetails anti-Androgen Receptor Antikörper

Bindungsspezifität: AA 207-221, pSer213

Spezifität: In IGF-1 stimulated LNCaP cells (passage number 38), a ~110 kD band was observed. Please see Lin et al. 2003 for additional details. The serine phosphorylation site recognized by this has been alternatively referred to Ser213 (Lee and Chang, 2003) and Ser210 (Lin et al, 2003). Variations in denotation can arise from how the sequence is counted in various GenBank accession numbers. The site is denoted as Ser213 in GenBank Accession No. A39248, which was used to design the immunogen.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Baboon, Monkey, Marmoset (100%) Gorilla, Bat, Panda (93%) Dog, Bovine, Cat, Rabbit, Horse, Pig, Guinea pig (87%) Mouse, Rat, Hamster (80%).

Aufreinigung: Protein G purified

Immunogen: This antibody was developed against a synthetic peptide corresponding to amino acids 207-221 (GRAREAS*GAPTSSKD) of human androgen receptor, containing the serine 213 phosphorylation site: GenBank Accession No. A39248. Note: S* refers to phosphorylated serine in the peptide sequence. Percent identity by BLAST analysis: Human, Chimpanzee, Baboon, Monkey, Marmoset (100%), Gorilla, Bat, Panda (93%), Dog, Bovine, Cat, Rabbit, Horse, Pig, Guinea pig (87%), Mouse, Rat, Hamster (80%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 - 4 μg/mL)

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Short term: 4°C
Long term: -70°C.

Details zu Androgen Receptor

Target: Androgen Receptor (AR)

Andere Bezeichnung: AR / Androgen Receptor

Hintergrund: Name/Gene ID: AR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: AR, Androgen receptor, Dihydrotestosterone receptor, DHTR, AIS, KD, NR3C4, HUMARA, SBMA, TFM, SMAX1, HYSP1

Gen-ID: 367

UniProt: P10275

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding