SOCS3 Antikörper

Produktnummer ABIN207073

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SOCS3 in WB und Inhibition. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SOCS3 Antikörper (ABIN207073)

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOCS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Blocking Antibody (Inhibition)

Klon: SO1

Produktdetails anti-SOCS3 Antikörper

Spezifität: The cytokine signaling is known to be regulated by a negative feedback regulator called suppressor of cytokine signaling (SOCS) inhibitors family. Members of the SOCS family have been identified due to their marked homology on the SH2 domain and a unique conserved motif referred to as the SOCS box. Expression of SOCS3 is transiently induced in a variety of immune and inflammatory situations by a wide variety of cytokines. SOCS3 is also involved in growth hormone function, leptin and insulin signaling. SOCS3 inhibits Janus kinase (JAK) tyrosine kinase activity

Aufreinigung: Protein A purified

Immunogen: Full-length SOCS3 protein.

Type of Immunogen: Recombinant protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Inhb, WB

Usage: Western Blotting: Positive control - HeLa human cervix carcinoma cell line. Sample preparation: Resuspend approx. 50 mil. cells in 1 mL cold Lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl  pH 8.2, 50 mM NaF including Protease inhibitor Cock

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Details zu SOCS3

Target: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Andere Bezeichnung: SOCS3

Hintergrund: Name/Gene ID: SOCS3

Synonyms: SOCS3, Cish3, Cytokine-induced SH2 protein 3, CIS-3, CIS3, SSI-3, STAT-induced STAT inhibitor 3, SSI3, ATOD4, SOCS-3

Gen-ID: 9021

UniProt: O14543

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C