C7 Antikörper (C-Term)
Kurzübersicht für C7 Antikörper (C-Term) (ABIN206670)
Target
Alle C7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Recognizes complement component 7 (C7), a 110 kD glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that Does not recognize membrane bound complement membrane attack complex. Inhibits lysis of sensitized sheep erythrocytes.
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Aufreinigung
- Protein A purified
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Immunogen
- Purified human C7.
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Isotyp
- IgG1
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Applikationshinweise
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Approved: ELISA, Func, WB
Not recommended for: IHC-P -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- BBS, 0.1 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- C7 (Complement Component C7 (C7))
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Andere Bezeichnung
- Complement C7
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Hintergrund
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Name/Gene ID: C7
Subfamily: Complement Component
Synonyms: C7, Complement C7, Complement component 7, Complement component C7 -
Gen-ID
- 730
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UniProt
- P10643
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Pathways
- Komplementsystem
Target
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