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CD80 Antikörper

CD80 Reaktivität: Maus FACS, IHC, IHC (fro) Wirt: Ratte Monoclonal RM80 unconjugated

Produktnummer ABIN206612

Datenblatt (PDF)

Target Alle CD80 Antikörper anzeigen

CD80
Reaktivität
151

109

46

8

6

6

1

1

1
Maus
Wirt
92

81

21

21

19

2

1
Ratte
Passende Sekundärantikörper
Klonalität
154

80

2
Monoklonal
Konjugat
97

19

19

16

12

5

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD80 Antikörper ist unkonjugiert
Applikation
139

93

69

39

39

25

14

13

13

13

11

10

10

6

5

4

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.

Aufreinigung

Protein G purified

Immunogen

BCL1 cells expressing CD80.

Klon

RM80

Isotyp

IgG2a

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CD80 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (AA 38-246) antibody
CD80 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC

anti-CD80 (CD80) (AA 251-321) antibody
CD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 APC

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PE

anti-CD80 (CD80) antibody
CD80 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 2A2 unconjugated

Applikationshinweise

Approved: Flo (1:10 - 1:50), IHC, IHC-Fr

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Kommentare

Target Species of Antibody: Mouse

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Target

CD80

Andere Bezeichnung

CD80 / B7 (CD80 Produkte)

Hintergrund

Name/Gene ID: CD80

Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1

Gen-ID

941

UniProt

P33681

Pathways

T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints