CD226 Antikörper (Biotin)

Produktnummer ABIN206456

Der Maus-Monoklonal Anti-CD226-Antikörper wurde für FACS und IP validiert. Er ist geeignet zum Nachweis von CD226 in Proben aus Human. }

Kurzübersicht für CD226 Antikörper (Biotin) (ABIN206456)

Target: CD226

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD226 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Produktdetails anti-CD226 Antikörper (Biotin)

Spezifität: Recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. XXX recommend the use of MCA2257XZ for functional studies.

Aufreinigung: Protein G purified

Immunogen: Human cytotoxic T lymphocyte clone.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1 - 1:10), IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Method sheets are available on request.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1.0 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD226

Target: CD226

Andere Bezeichnung: DNAM-1 / CD226

Hintergrund: Name/Gene ID: CD226

Synonyms: CD226, Adhesion glycoprotein, CD226 Molecule, CD226 antigen, DNAM-1, DNAM1, DNAX accessory molecule-1, TLiSA1, PTA1, DNAX accessory molecule 1

Gen-ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints