APAF1 Antikörper (AA 12-28)
Kurzübersicht für APAF1 Antikörper (AA 12-28) (ABIN205853)
Target
Alle APAF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 12-28
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Spezifität
- Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. AHP487 recognizes a 130kD band in Western blots.
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Aufreinigung
- Affinity purified
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Immunogen
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Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 ( AA 12-28 ).
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
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Applikationshinweise
- Approved: IHC, IHC-P, WB (1:1000 - 1:2000)
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing. Store undiluted.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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Andere Bezeichnung
- APAF1 / APAF-1
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Hintergrund
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Name/Gene ID: APAF1
Family: Apoptosis
Synonyms: APAF1, APAF-1, CED4, KIAA0413 -
Gen-ID
- 317
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UniProt
- O14727
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Pathways
- p53 Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Tube Formation, Positive Regulation of Endopeptidase Activity
Target
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