IGFBP7 Antikörper

Produktnummer ABIN205804

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IGFBP7 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IGFBP7 Antikörper (ABIN205804)

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGFBP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IGFBP7 Antikörper

Spezifität: Recognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumor types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol.

Aufreinigung: Purified

Immunogen: Recombinant human IGFBP-7.

Type of Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 2 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: ELISA: LS-C42599 may be used in an indirect ELISA or as a capture reagent in sandwich ELISA.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.

Konzentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.2.

Details zu IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Andere Bezeichnung: IGFBP7 / TAF

Hintergrund: Name/Gene ID: IGFBP7

Synonyms: IGFBP7, AGM, FSTL2, IGFBP-7v, IGFBP-rP1, IBP-7, Angiomodulin, RAMSVPS, MAC25 protein, PSF, TAF, Tumor-derived adhesion factor, IGF-binding protein 7, IGFBP-7, IGFBPRP1, MAC25, PGI2-stimulating factor

Gen-ID: 3490

Pathways: Growth Factor Binding