C3 Antikörper (FITC)

Produktnummer ABIN1991903

Der Kaninchen Polyklonal Anti-C3-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, C3 in Proben von Maus zu detektieren.

Kurzübersicht für C3 Antikörper (FITC) (ABIN1991903)

Target: C3 (Complement Component 3 (C3))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C3 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-C3 Antikörper (FITC)

Aufreinigung: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant mouse Complement C3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working concentration should be determinde by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Upon delivery aliquot and store at -20 °C or -80 °C.

Details zu C3

Target: C3 (Complement Component 3 (C3))

Andere Bezeichnung: Complement C3

Hintergrund: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform hasB-cell stimulatory activity. Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.
Synonyms: HSE-MSF,ASP,C3adesArg,C3

UniProt: P01027

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling