Myeloperoxidase Antikörper

Produktnummer ABIN1981877

Der Maus Monoklonal Anti-Myeloperoxidase-Antikörper wurde für ELISA und FACS validiert. Er ist geeignet, Myeloperoxidase in Proben von Human zu detektieren.

Kurzübersicht für Myeloperoxidase Antikörper (ABIN1981877)

Target: Myeloperoxidase (MPO)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Myeloperoxidase Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: MPO421-8B2

Produktdetails anti-Myeloperoxidase Antikörper

Verwendungszweck: Anti-Hu Myeloperoxidase Purified

Spezifität: The mouse monoclonal antibody MPO421-8B2 recognizes human myeloperoxidase, a heme protein present in intracellular granules of myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Human myeloperoxidase

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Do not use after expiration date stamped on vial label.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu Myeloperoxidase

Target: Myeloperoxidase (MPO)

Andere Bezeichnung: Myeloperoxidase

Hintergrund: Myeloperoxidase,Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.,MPO

Gen-ID: 4353

UniProt: P05164

Pathways: Chromatin Binding