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PTK2B Antikörper (Tyr402)

PTK2B Reaktivität: Human, Maus, Ratte WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN197440
  • Target Alle PTK2B Antikörper anzeigen
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    Bindungsspezifität
    • 24
    • 23
    • 17
    • 15
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr402
    Reaktivität
    • 116
    • 115
    • 97
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 145
    • 15
    • 3
    Kaninchen
    Klonalität
    • 140
    • 23
    Polyklonal
    Konjugat
    • 75
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Dieser PTK2B Antikörper ist unkonjugiert
    Applikation
    • 123
    • 59
    • 44
    • 40
    • 39
    • 25
    • 13
    • 12
    • 9
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    This antibody AP02719PU detects endogenous levels of total Pyk2 protein.
    Aufreinigung
    Immunoaffinity Chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).
    Top Product
    Discover our top product PTK2B Primärantikörper
  • Applikationshinweise
    Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
    Andere Bezeichnung
    FAK2 / PTK2B (PTK2B Produkte)
    Synonyme
    CADTK antikoerper, CAKB antikoerper, FADK2 antikoerper, FAK2 antikoerper, PKB antikoerper, PTK antikoerper, PYK2 antikoerper, RAFTK antikoerper, CAKbeta antikoerper, E430023O05Rik antikoerper, Raftk antikoerper, Pyk2 antikoerper, fak1b antikoerper, ptk2.2 antikoerper, ptk2b antikoerper, si:ch1073-355e8.1 antikoerper, protein tyrosine kinase 2 beta antikoerper, PTK2 protein tyrosine kinase 2 beta antikoerper, protein tyrosine kinase 2aa antikoerper, PTK2B antikoerper, Ptk2b antikoerper, ptk2aa antikoerper
    Hintergrund
    PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.Synonyms: CADTK, CAK-beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, PYK2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, RAFTK, Related adhesion focal tyrosine kinase
    Gen-ID
    2185
    NCBI Accession
    NP_004094
    UniProt
    Q14289
    Pathways
    EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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