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PRKDC Antikörper (pThr2609)

PRKDC Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN196898
  • Target Alle PRKDC Antikörper anzeigen
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    Bindungsspezifität
    • 26
    • 13
    • 12
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr2609
    Reaktivität
    • 163
    • 86
    • 47
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 151
    • 23
    • 3
    • 2
    Kaninchen
    Klonalität
    • 148
    • 31
    Polyklonal
    Konjugat
    • 91
    • 11
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser PRKDC Antikörper ist unkonjugiert
    Applikation
    • 79
    • 67
    • 56
    • 30
    • 30
    • 28
    • 27
    • 24
    • 15
    • 13
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Spezifität
    DNA PKcs (phospho-Thr2609) antibody detects endogenous levels of DNA PKcs only when phosphorylated at threonine 2609.
    Aufreinigung
    Immunoaffinity chromatography using epitope-specific phosphopeptide.
    Immunogen
    The antiserum was produced against synthesized phosphopeptide derived from human DNA PKcs around the phosphorylation site of threonine 2609 (V-E-TP-Q-A).
    Top Product
    Discover our top product PRKDC Primärantikörper
  • Applikationshinweise
    Suitable for use in Suitable for use in Western blot (1: 500-1: 1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
    Andere Bezeichnung
    DNA-PKcs / PRKDC / XRCC7 (PRKDC Produkte)
    Hintergrund
    DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.Synonyms: DNA-dependent protein kinase catalytic subunit, DNPK1, HYRC, HYRC1, p460
    Gen-ID
    5591
    NCBI Accession
    NP_001075109
    UniProt
    P78527
    Pathways
    DNA Reparatur, Production of Molecular Mediator of Immune Response
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